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On a cruise ship sailing across the Atlantic, Dr. Peter Palma expects to treat passengers for minor ailments. But violence erupts as a vile affliction pits loved ones against each other. The brig fills with felons, the morgue with bodies, and the vacation becomes a nightmare. With the ship bearing down on New York, Peter must fight through his own delirium to neutralize the threat. But sometimes primal urges are impossible to resist.